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 Catalytic Electrophilic Thiocarbocyclization of Allenes

From : Our Group            Refresh Time : Oct. 28th, 2021

Congratulations! The publication of our group in Org. Lett., "Catalytic Electrophilic Thiocarbocyclization of Allenes" has been published recently (Quanbin Jiang #, Huimin Li #, Xiaodan Zhao* Org. Lett., 2021, 23, 8777−8782, # These authors contributed equally to this work).

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  An efficient approach via catalytic electrophilic thiocarbocyclization of allenes to construct indene-based sulfides with excellent regioselectivities is disclosed. The reactions were carried out at low temperatures by selenide catalysis in the presence of TMSOTf. Not only electrophilic arylthio reagents but also electrophilic alkylthio reagents worked well under these conditions. Furthermore, the method could be applied to intermolecular azidothiolation of allenes.

 

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