Publications
2024
48.
Xu, X.#; Qin, T.#; Huang, N.; Liao, L.*; Zhao, X.* Catalytic Enantioselective Electrophilic Difunctionalization of Unsaturated Sulfones. (# These authors contributed equally to this work)
Org. Lett. 2024, 26, 4514-4519.
47.
Qiu, W.#; Liao, L.*#; Xu, X.; Huang, H.; Xu, Y.; Zhao, X.* Catalytic 1,1-diazidation of alkenes. (# These authors contributed equally to this work)
Nat. Commun. 2024, 15, 3632.
Highlighted by Synform.
Highlighted by X-Mol.
46.
Huang, N.; Luo, J.; Liao, L.; Zhao, X.* Catalytic Enantioselective Aminative Difunctionalization of Alkenes.
J. Am. Chem. Soc. 2024, 146, 7029-7038.
Highlighted by Synfacts.
Highlighted by Chemical Deep Ploughing Hall.
Highlighted by X-Mol.
45.
Jiang, Q.; Luo, J.; Zhao, X.* Enantioselective cross-dehydrogenative coupling enabled by organocatalysis.
Green Chem. 2024, 26, 1846-1875.
2023
44.
Liang, Y.#; Huang, H.#; Huang, N.#; Liao, L.*; Zhao, X.* Catalytic Enantioselective Construction of Chiral γ-Azido Nitriles through Nitrile Group-Promoted Electrophilic Reaction of Alkenes. (# These authors contributed equally to this work)
Org. Lett. 2023, 25, 6757-6762.
43.
Huang, N.; Liao, L.; Zhao, X.* Intermolecular Hydrazinative Halogenation of Alkenes with Potassium Halides as Nucleophilic Halogen Sources: Modular Entry to Phenelzine Derivatives.
Org. Lett. 2023, 25, 6587-6592.
Highlighted by Organic Chemistry Portal.
42.
Liu, P.; Zhong, F.; Liao, L.; Tan, W.*; Zhao, X.* Progress in the Construction of Spirocyclohexadienone Derivatives via Alkyne-involving Dearomatization.
Chin. J. Org. Chem. 2023, 43, 4019-4035.
41.
Zhang, Y.; Wu, J.; Qiu, W.; Liao, L.*; Wang, B.; Zhao, X.* Lewis Acid-Mediated Electrophilic Thiolative Difunctionalization of Enimides: Rapid Access to β-Amino Sulfides.
Org. Lett. 2023, 25, 5173-5178.
2022
40.
Liang, Y.; Jiao, H.; Zhang, H.; Wang, Y.-Q. Zhao, X.* Chiral Chalcogenide-Catalyzed Enantioselective Electrophilic Hydrothiolation of Alkenes.
Org. Lett. 2022, 24, 7210-7215.
39.
Liao, L.; Xu, X.; Ji, J.; Zhao, X.* Asymmetric Intermolecular Iodinative Difunctionalization of Allylic Sulfonamides Enabled by Organosulfide Catalysis: Modular Entry to Iodinated Chiral Molecules.
J. Am. Chem. Soc. 2022, 144, 16490-16501.
Highlighted by Chem Catalysis,Synfacts, CJOC.
Highlighted by School of Chemistry,SYSU.
Highlighted by Chemical Valley,Chem-Station.
38.
Liao, L.; Zhao, X.* Indane-Based Chiral Aryl Chalcogenide Catalysts: Development and Applications in Asymmetric Electrophilic Reactions.
Acc. Chem. Res. 2022, 55, 2439-2453.
Highlighted by School of Chemistry,SYSU.
37.
Wei, W.; Zhao, X.* Organoselenium-Catalyzed Cross-Dehydrogenative Coupling of
Alkenes and Azlactones.
Org. Lett. 2022, 24, 1780-1785.
36.
Cui, F.-H.#; Hua, Y.#; Lin, Y.-M.*; Fei, J.; Gao, L.-H.; Zhao, X.; Xia, H.* Selective Difunctionalization of Unactivated Aliphatic Alkenes Enabled by a Metal–Metallaaromatic Catalytic System. (# These authors contributed equally to this work)
J. Am. Chem. Soc. 2022, 144, 2301-2310.
35.
Zhong, F.; Zhao, X.* Selective Transformations of Carbonyl Derivatives via Selenium Catalysis.
Chin. J. Org. Chem. 2022, 42, 314-315.
Invited contribution.
2021
34.
Jiang, Q.#; Li, H.#; Zhao, X.* Catalytic Electrophilic Thiocarbocyclization of Allenes.(# These authors contributed equally to this work)
Org. Lett. 2021, 23, 8777-8782.
33.
Liao, L.; Zhao, X.* Modern Organoselenium Catalysis: Opportunities and Challenges.
Synlett 2021, 32, 1262-1268.
Invited contribution as part of the Cluster: Perspectives on Organoheteroatom and Organometallic Chemistry
32.
Luo, J.; Zhang, Y.; Zhong, F.; Zhao, X.* Catalytic Enantioselective Construction of Chiral Benzo-Fused N-Heterocycles through Friedel-Crafts-Type Electrophilic Chlorination.
CCS Chem. 2021, 3, 1363-1375.
31.
Zhang, Y.; Liang, Y.; Zhao, X.* Chiral Selenide-Catalyzed, Highly Regio- and Enantioselective Intermolecular Thioarylation of Alkenes with Phenols.
ACS Catal. 2021, 11, 3755-3761.
Highlighted by Synfacts.
30.
Liao, L.; Zhao, X.* Selenium-Catalyzed Functionalization of Alkynes.
Chem. Lett. 2021, 50, 1104-1113.
Invited contribution.
Selected as the Inside Cover.
29.
Jiang, Q.; Zhao, X.* Chiral Bifunctional Chalcogenide-Catalyzed Enantioselective Electrophilic Thiofunctionalization of Alkenes.
Chin. J. Org. Chem. 2021, 41, 443-454.
Invited contribution.
Selected as the Cover.
2020
28.
Guo, R.; Liu, Z.; Zhao, X.* Efficient Synthesis of P-Chirogenic Compounds Enabled by Chiral Selenide-Catalyzed Enantioselective Electrophilic Aromatic Halogenation.
CCS Chem. 2020, 2, 2617-2628.
Selected as the Author Spotlight.
27.
Wei, W.; Zhao, X. Selenopyrylium and Benzoselenopyrylium Salts (Uptate 2020).
Science of Synthesis Knowledge Updates, 2020, 3, 435-458.
26.
Jiang, Q.; Liang, Y.; Zhang, Y.; Zhao, X.* Chalcogenide-Catalyzed Intermolecular Electrophilic Thio- and Halofunctionalization of gem-Difluoroalkenes: Construction of Diverse Difluoroalkyl Sulfides and Halides.
Org. Lett. 2020, 22, 7581-7587.
25.
Xu, Y.; Liao, L.; Zhao, X.* Progress in the Synthesis of Aza-Heterocyclic Compounds via Selenium-π-Acid Catalysis.
Chemistry (Huaxue Tongbao) 2020, 83, 970-976.
24.
Liao, L.; An, R.; Li, H.; Xu, Y.; Wu, J.-J.; Zhao, X.* Catalytic Access to Functionalized Allylic gem‐Difluorides via Fluorinative Meyer‐Schuster‐Like Rearrangement.
Angew. Chem. Int. Ed. 2020, 59, 11010-11019.
Selected as Hot Paper.
Highlighted by Synfacts.
Highlighted by Chin. J. Org. Chem.
Highlighted by ChemBeanGo.
23.
Liang, Y.; Ji, J.; Zhang, X.; Jiang, Q.; Luo, J.; Zhao, X.* Enantioselective Construction of Axially Chiral Amino Sulfide Vinyl Arenes by Chiral Sulfide‐Catalyzed Electrophilic Carbothiolation of Alkynes.
Angew. Chem. Int. Ed. 2020, 59, 4959-4964.
Highlighted by X-MOL.
2019
22.
Wei, W.; Liao, L.; Qin, T.; Zhao, X.* Access to Saturated Thiocyano-Containing Azaheterocycles via Selenide-Catalyzed Regio- and Stereoselective Thiocyanoaminocyclization of Alkenes.
Org. Lett. 2019, 21, 7846-7850.
21.
Liang, Y.; Zhao, X.* Enantioselective Construction of Chiral Sulfides via Catalytic Electrophilic Azidothiolation and Oxythiolation of N-Allyl Sulfonamides.
ACS Catal. 2019, 9, 6896-6902.
Highlighted by Yan Zhi Cheng Li.
20.
Li, H.; Liao, L.; Zhao, X.* Organoselenium-Catalyzed Aza-Wacker Reactions: Efficient Access to Isoquinolinium Imides and an Isoquinoline N-Oxide.
Synlett 2019, 30, 1688-1692.
Invited contribution as part of the Cluster: Organosulfur and Organoselenium
Compounds in Catalysis
Highlighted by Organic Chemistry Portal.
19.
Cao, Q.; Luo, J.; Zhao, X.* Chiral Sulfide Catalysis for Desymmetrizing Enantioselective Chlorination.
Angew. Chem. Int. Ed. 2019, 58, 1315-1319.
Selected as Hot Paper.
Selected as the Inside Back Cover.
Highlighted by Yan Zhi Cheng Li.
Highlighted by Synfacts.
18.
Qin, T.; Jiang, Q.; Ji, J.; Luo, J.; Zhao, X.* Chiral selenide-catalyzed enantioselective synthesis of trifluoromethylthiolated 2,5-disubstituted oxazolines.
Org. Biomol. Chem. 2019, 17, 1763-1766.
Invited contribution to the themed collections: New Talent
2018
17.
An, R.; Liao, L.; Liu, X.; Song, S.; Zhao, X.* Acid-catalyzed oxidative cleavage of S–S and Se–Se bonds with DEAD: efficient access to sulfides and selenides.
Org. Chem. Front. 2018, 5, 3557-3561.
16.
Xu, J.#; Zhang, Y.#; Qin, T.; Zhao, X.* Catalytic Regio- and Enantioselective Oxytrifluoromethylthiolation
of Aliphatic Internal Alkenes by Neighboring Group Assistance.(# These authors contributed equally to this work)
Org. Lett. 2018, 20, 6384–6388.
15.
Liao, L.; Zhang, H.; Zhao, X.* Selenium-π-Acid Catalyzed Oxidative Functionalization of Alkynes: Facile Access to Ynones and Multisubstituted Oxazoles.
ACS Catal. 2018, 8, 6745−6750.
Highlighted by Yan Zhi Cheng Li.
14.
Liu, X.; Liang, Y.; Ji, J.; Luo, J.; Zhao, X.* Chiral Selenide-Catalyzed Enantioselective Allylic Reaction and Intermolecular Difunctionalization of Alkenes: Efficient Construction of C-SCF3 Stereogenic Molecules.
J. Am. Chem. Soc. 2018, 140, 4782−4786.
Highlighted by Chin. J. Org. Chem..
Highlighted by Hua Xue Jia.
13.
Luo, J.; Cao, Q.; Cao, X.*; Zhao, X.* Selenide-catalyzed enantioselective synthesis of
trifluoromethylthiolated tetrahydronaphthalenes by
merging desymmetrization and
trifluoromethylthiolation.
Nat. Commun. 2018, 9, 527.
12.
Guo, R.; Huang, J.; Zhao, X.* Organoselenium-Catalyzed Oxidative Allylic Fluorination with Electrophilic N–F Reagent.
ACS Catal. 2018, 8, 926–930.
2017
11.
Zhu, Z.; Luo, J.; Zhao, X.* Combination of Lewis Basic Selenium Catalysis and Redox Selenium Chemistry: Synthesis of Trifluoromethylthiolated Tertiary Alcohols with Alkenes.
Org. Lett. 2017, 19, 4940–4943.
10.
Luo, J.; Liu, Y.; Zhao, X.* Chiral Selenide-Catalyzed Enantioselective Construction of Saturated Trifluoromethylthiolated Azaheterocycles.
Org. Lett. 2017, 19, 3434–3437.
9.
Guo, R .; Liao, L.; Zhao, X.* Electrophilic Selenium Catalysis with Electrophilic N-F Reagents as the Oxidants.
Molecules 2017, 22, 835.
Invited contribution to the Special Issue Celebrating Two Centuries of Research in Selenium Chemistry: State of the Art and New Prospectives
8.
Liao, L.; Guo, R.; Zhao, X.* Organoselenium-Catalyzed Regioselective C-H Pyridination of
1,3-Dienes and Alkenes.
Angew. Chem. Int. Ed. 2017, 56, 3201–3205.
Selected as the Inside Back Cover.
Highlighted by Chin. J. Org. Chem..
Highlighted by Synfacts.
7.
Luo, J .; Liu, X.; Zhao, X.* Development of Chalcogenide Catalysts towards Trifluoromethylthiolation.
Synlett 2017, 28, 397-401.
Invited Synpacts Highlight.
2016
6.
Wu, J.-J.; Xu, J.; Zhao, X.* Selenide-Catalyzed Stereoselective Construction of Tetrasubstituted Trifluoromethylthiolated Alkenes with Alkynes.
Chem. Eur. J. 2016, 22, 15265–15269.
5.
Liu, X.; An, R.; Zhang, X.; Luo, J.; Zhao, X.* Enantioselective Trifluoromethylthiolating Lactonization Catalyzed by
an Indane-Based Chiral Sulfide.
Angew. Chem. Int. Ed. 2016, 55, 5846–5850.
Selected as the Inside Back Cover.
Highlighted by Chin. J. Org. Chem..
Highlighted by X-MOL.
4.
Guo, R.; Huang, J.; Huang, H.; Zhao, X.* Organoselenium-Catalyzed Synthesis of Oxygen- and Nitrogen-Containing Heterocycles.
Org. Lett. 2016, 18, 504-507.
Highlighted by Organic Chemistry Portal.
2015
3.
Zhang, X.; Guo, R.; Zhao, X.* Organoselenium-catalyzed synthesis of indoles through intramolecular C-H amination.
Org. Chem. Front. 2015, 2, 1334-1337.
2.
Luo, J.; Zhu, Z.; Liu, Y.; Zhao, X.* Diaryl Selenide Catalyzed Vicinal Trifluoromethylthioamination of Alkenes.
Org. Lett. 2015, 17, 3620-3623.
Highlighted by X-MOL.
1.
Deng, Z.; Wei, J.; Liao, L.; Huang, H.; Zhao, X.* Organoselenium-Catalyzed, Hydroxy-Controlled Regio- and Stereoselective Amination of Terminal Alkenes: Efficient Synthesis of 3-Amino Allylic Alcohols.
Org. Lett. 2015, 17, 1834-1837.
Highlighted by Organic Chemistry Portal.
2013 and before
14. Zhao, X.; Glover, G. S.; Oberg, K. M.; Dalton, D. M.; Rovis, T.* SNAr-Derived Decomposition By-products Involving Pentafluorophenyl Triazolium Carbenes.
Synlett. 2013, 24, 1229-1232.
13. Zhao, X.; Ruhl, K. E.; Rovis, T.* N-Heterocyclic Carbene-Catalyzed Asymmetric Oxidative Hetero-Diels-Alder Reactions with Simple Aliphatic Aldehydes.
Angew. Chem. Int. Ed. 2012, 51, 12330-12333.
12. Zhao, X.; DiRocco, D. A.; Rovis, T.* N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis of trans-γ-Lactams.
J. Am. Chem. Soc. 2011, 133, 12466-12469.
11. Zhao, X.; Dong, V. M.* Reductive Elimination from Pd(IV) Sulfinate Complexes.
Angew. Chem. Int. Ed. 2011, 50, 932-934.
10. Yeung, C. S.; Zhao, X.; Borduas, N.; Dong, V. M.* Pd-Catalyzed ortho-Arylation of Phenylacetamides, Benzamides, and Anilides with Simple Arenes using Sodium Persulfate.
Chem.Sci. 2010, 1, 331-336.
9. Zhao, X.; Yeung, C. S.; Dong, V. M.* Palladium-Catalyzed ortho-Arylation of O-Phenylcarbamates with Simple Arenes and Sodium Persulfate.
J. Am. Chem. Soc. 2010, 132, 5837-5844.
8. Zhao, X.; Dimitrijević, E.; Dong,V. M.* Palladium-Catalyzed C–H Bond Functionalization with Arylsulfonyl Chlorides.
J. Am. Chem. Soc. 2009, 131, 3466-3467.
7. Zhao, X.; Yu, Z.* Rhodium-Catalyzed Regioselective C–H Functionalization via Decarbonylation of Acid Chlorides and C–H Bond Activation under Phosphine-Free Conditions.
J. Am. Chem. Soc. 2008, 130, 8136-8137.
6. Zhao, X.; Yu, Z.;* Xu, T.; Wu, P.; Yu, H. Novel Brønsted Acid-Catalyzed Three-Component Alkylation of Indoles with N-Phenylselenophthalimide and Styrenes.
Org. Lett. 2007, 9, 5263-5266.
5. Tan, W.; Zhao, X.; Yu, Z.* Synthesis and Structural Characterization of Ruthenium(II) Complexes Bearing Phosphine-Pyrazolyl Based Tripod Ligands.
J. Organomet. Chem. 2007, 692, 5395-5402.
4. Zhao, X.; Alper, H.;* Yu, Z.* Stereoselective Hydroxycarbonylation of Vinyl Bromides to the Corresponding α,β-Unsaturated Carboxylic Acids in the Ionic Liquid [BMIM]PF6.
J. Org. Chem. 2006, 71, 3988-3990.
3. Zhao, X.; Yu, Z.;* Yan, S.; Wu, S.; Liu, R.; He, W.; Wang, L. Ruthenium(III) Chloride Catalyzed Efficient Synthesis of Unsymmetrical Diorganyl Selenides via Cleavage of Dibenzyl and Diphenyl Diselenides in the Presence of Zinc.
J. Org. Chem. 2005, 70, 7338-7341.
2. Zhao, X.; Yu, Z.;* Zeng, F.; Chen, J.; Wu, X.; Wu, S.; Xiao, W.-J.;* Zheng, Z.Highly Efficient Route to Diselenides from the Reactions of Imines and Selenium in the Presence of Carbon Monoxide and Water.
Adv. Synth. Catal. 2005, 347, 877-882.
1. Chen, J.; Ling, G.; Yu, Z.;* Zeng, F.; Wu, S.; Zhao, X.;Wu, X.; Lu, S.* N-Arylamides from Selenium-Catalyzed Reactions of Nitroaromatics and Amides in the Presence of Carbon Monoxide and Mixed Organic Base.
Adv. Synth. Catal. 2004, 346, 1267-1270.