Organoselenium-Catalyzed Cross-Dehydrogenative Coupling of Alkenes and Azlactones
Congratulations! The publication of our group in Org. Lett., "Organoselenium-Catalyzed Cross-Dehydrogenative Coupling of Alkenes and Azlactones" has been published recently (Wei Wei, Xiaodan Zhao* Org. Lett., 2022, 24, 1780–1785).
The carbon–carbon bond-forming cross-dehydrogenative coupling of alkenes and azlactones by organoselenium catalysis involving a high-valent para-methoxyphenyl selenium species is disclosed. A series of α,α-disubstituted α-amino acid derivatives were obtained in excellent regioselectivities through vinyl or allylic C–H functionalization. The generality of the method was elucidated by the cross-coupling of an alkene with an oxindole and the direct functionalization of electron-rich arenes with azlactones.
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